Linoleic acid is an
unsaturated fatty acid. Linoleic acid (LA) is a naturally occurring fatty acid
found in beef ,dairy products and oils like safflower and soy oil, . Linoleic
acid is one of the two essential fatty acids (the other is linolenic acid). Linoleic
acid is an omega-6 fatty acid, meaning that it is unsaturated, with a double bond
occurring at the sixth carbon atom from the omega end of the molecule.
Linoleic acid-- CH 3 (CH2)4CH=CHCH2CH=CH(CH2)7COOH
,
Conjugated linoleic acid (CLA) is a mixture of positional
and geometric isomers of linoleic acid, which is found preferentially in dairy
products and meat. Preliminary studies indicate that CLA is a powerful anticancer
agent in the rat breast tumor model with an effective range of 0.1-1% in the diet.
While linoleic acid is found in the diet in vegetable oils, the conjugated variety,
CLA, is found primarily in meat and dairy products.
Conjugated
linoleic acid is unique because it is present in food from animal sources, and
its anticancer efficacy is expressed at concentrations close to human consumption
levels. See:Conjugated linoleic acid and atherosclerosis in rabbits Lee K.N.;
Kritchevsky D.; Pariza M.W. Food Research Institute, Dept. Food Microbiology/Toxicology,
University of Wisconsin-Madison, 1925 Willow Drive, Madison, WI 53706 USA Atherosclerosis
(Ireland), 1994, 108/1 (19-25)